International Journal of Current Medical and Biological Sciences 2023-10-11T22:48:35+03:00 Assoc. Prof. Mustafa Begenc Tascanov Open Journal Systems <p><strong>The international journal of <span style="font-size: 0.875rem;">current </span>medical and biological sciences (e-ISSN 2791-8815)</strong><span style="font-size: 0.875rem;"> is published in accordance with the principles of independent, impartial and double-blind reviewer. The journal is published 3 times a year. No fee is charged from the authors during the article evaluation and publication process.</span></p> <p>It publishes clinical and experimental studies, editorial articles, technical and educational reviews, clinical case reports, original images, letters to the editor, and congress abstracts that contribute to general medicine and academic studies. It is published as open access in the English language.</p> Bilateral Ureteral Involvement in Endometriosis - Case Report 2023-07-15T18:12:45+03:00 Musab Köse <p><span style="font-weight: 400;">Ureteral endometriosis is a rare pathology that, if left untreated, can lead to renal damage. In this case, we present a 48-year-old female patient with a rare persistent bilateral ureteral obstruction and hydroureteronephrosis.&nbsp;</span></p> <p><span style="font-weight: 400;">Imaging revealed the obstruction but was not helpful in illuminating</span> <span style="font-weight: 400;">the etiology. In the patient who underwent exploratory laparotomy, the affected ureter and surrounding fibrotic foci were resected, and ureteroneocystostomy was performed. During follow-up, the patient's clinical condition improved, and no recurrence was observed.</span></p> <p><span style="font-weight: 400;">Consequently, ureteral endometriosis is a rare pathology, and imaging may not be helpful in determining the etiology. It should be considered in the differential diagnosis of resistant obstructions. </span></p> 2023-10-26T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences Artificial Intelligence Evaluation of the Utility of HALP Score and Hematological Indicators in Estimating No-Reflow After Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction 2023-10-11T22:48:35+03:00 Rustem Yilmaz <p style="font-weight: 400;"><strong>Background: </strong>Acute Myocardial Infarction (AMI) is a leading cause of mortality globally, with ST-segment Elevation Myocardial Infarction (STEMI) being a specific type. The study aims to fill the gap in literature regarding the predictive utility of hematological parameters and the HALP score in the context of the "no-reflow" phenomenon in STEMI patients. To evaluate the predictive efficacy of hematological parameters and the HALP score in identifying the "no-reflow" phenomenon in STEMI patients undergoing Primary Percutaneous Coronary Intervention (PPCI) using Explainable AI (XAI) methodologies.</p> <p style="font-weight: 400;"><strong>Material and Methods: </strong>A retrospective observational design was used, involving 232 STEMI patients who underwent PPCI between January 2020 and September 2023. The cohort was subsequently dichotomized into two subsets based on the presence or absence of the no-reflow phenomenon. Data were collected on demographic variables, MI locations, and hematological parameters. The HALP score was calculated, and XGBoost machine learning models were developed and evaluated.</p> <p style="font-weight: 400;"><strong>Results: </strong>Statistically significant differences were observed in white blood cell count (WBC), monocyte (MO), neutrophil (NEU), platelet (PLT), albumin (ALB), and the MPV/LY ratio (MPVLR) between the 'NORMAL-REFLOW' and 'NO-REFLOW' categories. The XGBoost model showed good performance in the training set but had limitations in sensitivity in the test set.</p> <p style="font-weight: 400;"><strong>Conclusion: </strong>In this study, according to artificial intelligence analysis, the most important hematological parameter in predicting no-relow was MPVLR. However, in this study, HALP score was not found to be effective in predicting no-reflow. The study provides valuable insights into the predictive factors for reflow outcomes in STEMI patients. </p> <p style="font-weight: 400;"> </p> 2023-10-28T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences Tissue Oxygenation Change on Upper Extremities After Ultrasound-Guided Axillary Brachial Plexus Blockade; Prospective Observational Study 2023-08-23T15:42:38+03:00 maruf sürücü mahmut alp karahan şaban yalçın nuray altay evren büyükfırat aytekin yeşilay <p><strong>ABSTRACT </strong></p> <p><strong>Introduction</strong></p> <p>The aim of the study was to investigate whether tissue oxygen saturation (St02), is a reliable and objective method for assessing the adequacy of axillary blockade and to describe the time course of StO2 changes.</p> <p><strong>Materials and Methods</strong></p> <p>The study was approved by the Ethical Committee and met the Declaration of Helsinki criteria. In this prospective observational study, St02 was measured in 30 patients scheduled for elective hand surgery under axillary nerve block. Non-invasive StO2 -monitoring (In Spectra™ StO2, Hutchinson Technology Inc., Hutchinson, Minnesota, USA) was used in patients before ultrasound guided axillary brachial plexus blockade and during the first 30 minute of the blockade. To measure tissue oxygen saturation near-infrared light is emitted into the thenar tissue. In the light that is reflected from the tissue, the percentage of oxygenated haemoglobin is calculated by using the different absorption spectra of oxygenated and deoxygenated haemoglobin. Repeated measure ANOVA test for repeated measurement and paired sample t test were used for comparison of two hands StO2 levels.</p> <p><strong>Results</strong></p> <p>StO2 measurements were statistically increased in 1st,5th, 10th, 15th,20th,25th,30th minutes compared to baseline levels (p&lt; 0.05 for all comparisons). Mean StO2 levels of the hand with axillary brachial plexus blockade were statistically increased compared the levels of the hand StO2 without blockade in 15th,20th, 25th, 30th. minutes (p&lt; 0.05 for all comparisons).</p> <p><strong>&nbsp;</strong></p> <p><strong>&nbsp;</strong></p> <p><strong>Conclusion</strong></p> <p>There has been found a significant correlation between tissue StO2 values of two limbs using NIRS in axillary blockage operations of upper extremity.</p> 2023-11-06T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences Analysis of disturbution of bronchopulmonary segments in covid-19 patients 2023-08-08T08:37:29+03:00 Ayşe Gül Kabakci Yeşim Taşova Memduha Gülhal Bozkır <p>Objective: Imaging modalities are important in the correct treatment and diagnosis of COVID 19, which causes severe damage to lung tissue. Ground-glass opacity is the most commonly reported imaging finding of COVID-19 pneumonia. Therefore, we aimed to analyze the distribution of bronchopulmonary segments in patients with ground-glass opacities.</p> <p>Materials and Methods: We included tomography images of 93 patients who were diagnosed as COVID-19 positive during the period when COVID-19 vaccine studies had not yet started. Thorax CT images of patients with COVID-19 were examined in the axial line. In each slice, the presence of ground-glass image of the right and left lungs was examined segment by segment. All slices with ground-glass image were recorded for each patient according to the slices in the Radiopeadia program.</p> <p>Results: The mean age of patients with ground-glass opacity was 47.05±16.35 years (21-82), 45.77±16.15 years in men and 48.58±16.76 years in women. In addition, the mean age of 36 patients (19 males and 17 females) without ground glass opacity was 44.28±17.53 years. When the right and left lungs were compared by gender, the density of ground-glass opacity was 50.17% in men and 49.83% in women in the right lung, and 56.40% in men and 43.6% in women in the left lung. When the right and left lungs were compared, the presence of ground-glass opacities was observed in 56.18% of the right lung and 43.82% of the left lung. Conclusion: In our study, we found that most ground glass opacity appearance were observed in the lower lobe, right lung and in men. We think that this study will be a source of data on the course of the COVID 19 in the medium and long term.</p> <p>nüyoruz.</p> 2023-11-17T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences Can Bacteriophage Therapy Be an Alternative Solution Against Medicinal Leech Associated Infections? 2023-07-07T08:14:51+03:00 Mustafa Ünal Muhammed Emin Göktepe Mustafa Yasin Selçuk Onur Öztürk <p>Medicinal leeches are effective in many clinical conditions. But leech associated aeromonas&nbsp; infections are common and limits the benefits of leech therapy. Bacteriophages are specific bacteria hunting viruses that could be used effectively against target bacteria without side effects. There are 5 bacteriophages defined in the literature against aeromonas spp. which their clinical use in hiridotherapy associated infections could open a way for a safer and more effective usage of medicinal leeches.</p> 2023-08-13T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences The Usability of IVC Diameter, IVC Collapsibility Index and Snuffbox Resistive Index in the Management of Sepsis and Septic Shock Patients in the Emergency Department 2023-07-07T08:12:52+03:00 Serdar Özdemir <p>Hemodynamics is a science that studies the properties and rules of movement of blood and its components in the body. Oxygen delivery to tissues is an important component of peripheral and systemic circulatory hemodynamics. Peripheral and systemic circulation is the key point to achieving hemodynamic stability. Hemodynamic evaluation guides the admission of patients to the intensive care unit during the diagnosis and treatment process. IVC diameter, IVC collapsibility index, and snuffbox resistive index are new ultrasonographic parameters in the management of sepsis and septic shock patients in the emergency department</p> 2023-08-13T00:00:00+03:00 Copyright (c) 2023 International Journal of Current Medical and Biological Sciences