The Association of Demographic Data and Hematological Parameters with Causes of Death in Patients Following Cardiopulmonary Resuscitation in the Emergency Department

Cardiopulmonary Resuscitation and Its Relationship with Blood Values

Abstract

Background: Cardiopulmonary arrest, marked by the cessation of breathing and circulation, has high mortality rates. Cardiopulmonary resuscitation (CPR) outcomes are influenced by factors like arrest duration and underlying conditions. Inflammatory markers such as platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), and red cell distribution width (RDW) may predict mortality.

Materials and Methods: This retrospective study analyzed 142 patients who died after CPR in the Emergency Department of Harran University Training and Research Hospital (between January 1, 2018, and December 31, 2020) and 150 healthy controls. Hematological indices (WBC, PLR, LMR, RDW) and clinical data were compared using statistical tests, including ROC analysis.

Results: The patient group had a mean age of 58.99 ± 19.28 years. Heart failure (7.5%) and acute myocardial infarction (6.8%) were the leading causes of death. WBC, LMR, and RDW were significantly higher in the patient group, while PLR and platelet counts were lower (p<0.05). ROC analysis identified RDW (AUC: 0.670) and LMR (AUC: 0.707) as significant prognostic markers.

Conclusions: Elevated LMR and RDW values and reduced PLR and platelet counts may predict mortality in CPR patients.

Keywords: Cardiopulmonary Resuscitation, Mortality Inflammatory Markers, Lymphocyte-Monocyte Ratio, Red Cell Distribution Width