The Mediterranean Diet Effects on in-Stent Restenosis.

Mediterranean Diet and in-Stent Restenosis


  • Aliye Kuyumcu Süleyman Demirel University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Isparta
  • Yasin Özen Sivas Numune Hastanesi
  • Sebahat Ulusan Süleyman Demirel University, Faculty of Medicine, Isparta
  • Mevlüt Serdar Kuyumcu Süleyman Demirel University, Faculty of Medicine, Department of Cardiology, Isparta



In-stent restenosis, Mediterranean diet score, Coronary artery disease


Aim: There is evidence that Mediterranean diet nutrition can help prevent cardiovascular events and atherosclerosis, but research is limited. Despite advances in interventional techniques and medical treatments, as well as lower CVD mortality, increasing percutaneous coronary interventions have made in-stent restenosis (ISR) an important problem in interventional cardiology. The objective of this study is to assess the relationship between in-stent restenosis and the Mediterranean diet score.

Material and Methods: The diet quality of 100 patients with ISR and 100 patients without ISR was determined and compared using a scoring method (5, 6, 9, and 10 points) using the 'Mediterranean Diet Compliance Scale'.

Results: Patients with ISR had lower Mediterranean diet scores (odds ratio [OR]: 0.572, 95% confidence interval [CI]: (0.480-0.681), p<0.001). The ISR and Mediterranean diet score had a significant negative correlation (p<0.001, r = -0.679).

Conclusion: In our study, we found that patients who scored high on the Mediterranean diet had a lower risk of ISR, and there was also a negative correlation between the Mediterranean diet and ISR. It is the first study to look at the effects of the Mediterranean diet on patients with a previous percutaneous coronary intervention. This study, one of a few examining the relationship between the Mediterranean diet and ISR, may aid in understanding the pathophysiology of ISR.




How to Cite

Kuyumcu A, Özen Y, Ulusan S, Kuyumcu MS. The Mediterranean Diet Effects on in-Stent Restenosis.: Mediterranean Diet and in-Stent Restenosis. İJCMBS [Internet]. 2023 Apr. 30 [cited 2024 Feb. 22];3(2):74-81. Available from: